What is Histamine?

Histamine is involved in a variety of physiologic responses, such as inflammation, type I allergy, gastric acid secretion and neurotransmission. As a neurotransmitter histamine has been implicated in the regulation of numerous and important activities of the central nervous system such as arousal, cognition, circadian rhythms and neuroendocrine regulation. Histamine imbalances have been implicated in schizophrenia, depression, anxiety, behavioural disorders and autism.

Low Histamine

A patient with low histamine, termed histapenic, will have a tendency to accumulate excessive amounts of copper and have overmethylation. Both histamine depletion and copper excess may produce behavioural abnormalities.

Characteristics of Histapenia

  • Poor achiever
  • Religiosity
  • Poor motivation
  • Grandiosity
  • Depression
  • Easily frustrated
  • Self isolation
  • Undue suspicion
  • High anxiety and panic
  • Low libido/ Difficult orgasm
  • Nervousness
  • Overweight
  • Paranoia
  • Sleep Disorder
  • Self mutilation
  • Tinnitis
  • High pain threshold
  • Hirsutism
  • Hyperactive psychosis
  • Eczema/dry skin

High Histamine

A patient with high histamine, termed histadelia, will have a tendency to have a high metabolism, low copper, low zinc and undermethylation. Histadelia usually runs in families with the onset at around 20 years of age. A family history of depression and allergies is a strong indication of possible histadelia.

Characteristcs of Histadelia

  • Addictive behaviour
  • Blank mind
  • Catatonic psychosis
  • Cry, salivate and feel nauseated easily
  • Delusional
  • Diagnoses of OCD/ODD common
  • Fast metabolism
  • Frequent stomach aches, muscle cramps and back pains
  • Hearing blood rushing in head on pillow at night
  • Heat intolerant
  • High achiever before illness
  • High energy
  • High inner tension
  • High libido
  • High motivation
  • Large ears and long fingers and toes
  • Light sleeper
  • Low pain tolerance
  • Migraine headaches
  • Non Complience
  • Phobias
  • Seasonal allergies
  • Sneezes in bright sunlight
  • Social isolation
  • Strong willed